Is methotrexate(MTX) effective in treating Rheumatoid Arthritis(RA)? Patients
on MTX treatment for their RA are rather concerned about the effectiveness of
this drug and the potential side effects. Well then, in this passage, we’ll
explain it for you.
Methotrexate in the treatment of Rheumatoid Arthritis(RA): benefits and side
effects
Methotrexate is a potent drug. It mainly functions by interfering the way
cells utilize nutrients, thus inhibiting the immune activity and resisting
inflammation. The drug may slow the growth of cells in the synovial membrane
that line the joints and reduce progression of Rheumatoid Arthritis.
Over the past years, the treatment for RA has changed from conservative
therapy to the formation of idea that early, aggressive treatment is imperative.
Researches have indicated that early methotrexate treatment in RA may provide
the patients a better a result. Methotrexate is a long-term treatment in RA. The
drug can slow the progression of this disease, and steady improvement can be
seen in patients on this drug for months or years.
However, most of the fears are about the hidden toxic effects caused by use
of this drug, such as lung disease, anemia, etc. Liver damage is among the
potential threats since once the damage occurs, it is
irreversible. Therefore, tests are sometimes needed to monitor whether those
problems are occurring. Signs such as hair loss and mouth or skin soreness are
indicators of toxic reaction of methotrexate. In such cases, the drug should be
discontinued.
Nausea is a common side effects of methotrexate. The nausea can often
disappear on its own, or may be relieved after reducing the dosage,
Points to know
Because the drug may lead to birth defects, men planning to become fathers
and mothers being or planning to be pregnant should avoid using methotrexate.
The drug is also not suitable for people who drink a lot of alcohol because it
can greatly increase their risk of severe liver problem.
Methotrexate is one of the medications commonly prescribed to patients with
Rheumatoid Arthritis(RA). To keep updated with latest news on treatment of RA
and ways to control side effects, you may submit your information in the form
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read more about: The Effects of Methotrexate for Rheumatoid Arthritis (RA)
